Fig. 1 | Genetics in Medicine

Fig. 1

From: Clinical sensitivity of prenatal screening for cystic fibrosis via CFTR carrier testing in a United States panethnic population

Fig. 1

Clinical sensitivity for detecting cystic fibrosis, using a panel of 25 CFTR mutations in five racial/ethnic groups. Clinical sensitivity (the square of the proportion of detected disease-causing mutations) is the proportion of carrier couples or affected fetuses that can be identified and is shown on the vertical axis. Horizontal axis shows the American College of Medical Genetics recommended panel of 25 mutations. For each group, the mutations are added in order from most to least common within that group. The clinical sensitivity reported is considered a maximum, as analytic sensitivity is assumed to be 100%.

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