Fig. 5 | Genetics in Medicine

Fig. 5

From: Genomewide linkage scan in a multigeneration Caucasian pedigree identifies a novel locus for keratoconus on chromosome 5q14.3-q21.1

Fig. 5

Linkage results of chromosome 5 (penetrance = 0.5, phenocopy = 0.01) under pedigree scenario B. Each short line on the horizontal axis represents a marker corresponding to their locations. A, Initial scan, at ≈10 cM density. B, Fine mapping at 1 to 2 cM density in the region between D5S424 and D5S433. Name and position of each marker can be referenced the marker order on Table 2. LOD scores of each marker are plotted on the vertical axis.

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