Figure 3 | Genetics in Medicine

Figure 3

From: An integrated approach for classifying mitochondrial DNA variants: one clinical diagnostic laboratory’s experience

Figure 3

Use PolyPhen and SIFT to predict mtDNA mutations and variants. The dark shaded areas are proportions of mutations or variants predicted to be deleterious; the light shaded areas are variants predicted to be benign. LHON, Leber hereditary optic neuropathy; mtDNA, mitochondrial DNA; PolyPhen, polymorphism phenotyping; SIFT, sorting intolerant from tolerant.

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