Figure 1

Ascites cells of patient P27 were harvested before treatment. (a) Activity of COX-2 promoter was demonstrated by infecting cells in vitro with non-replicating chimeric Ad5Cox2L-luc1 adenovirus coding for luciferase. (b) In transduction analysis in vitro, chimeric Ad5/3luc1 showed 12-fold increase in gene delivery compared to Ad5luc1.