Table 2 Adverse events after single round of Ad5/3-cox2L-D24 treatment
Grade 1 | Grade 2 | Grade 3 | Grade 4 or 5 | |
|---|---|---|---|---|
General | ||||
Chills | 2 | 0 | 0 | 0 |
Dizziness | 1 | 2 | 0 | 0 |
Dyspnea | 0 | 1 | 0 | 0 |
Fatigue | 6 | 4 | 0 | 0 |
Fever | 6 | 3 | 0 | 0 |
Flu-like syndrome | 4 | 0 | 0 | 0 |
Metabolic or laboratory | ||||
ALT increased | 1 | 3 | 0 | 0 |
AST increased | 2 | 4 | 0 | 0 |
ALP increased | 0 | 1 | 0 | 0 |
Hyperbilirubinemia | 2 | 1 | 0 | 0 |
Hyperkalemia | 0 | 1 | 0 | 0 |
Hypokalemia | 0 | 0 | 1 | 0 |
Hyponatremia | 6 | 0 | 2 | 0 |
INR increased | 5 | 0 | 1 | 0 |
Cardiovascular | ||||
Hypertension | 3 | 0 | 0 | 0 |
Hematological | ||||
Hemoglobin decreased | 4 | 5 | 0 | 0 |
Leukocytopenia | 2 | 2 | 0 | 0 |
Thrombocytopenia | 2 | 0 | 1 | 0 |
Dermatological | ||||
Urticaria | 0 | 1 | 0 | 0 |
Gastrointestinal | ||||
Anorexia | 3 | 0 | 0 | 0 |
Ileus | 2 | 1 | 1 | 0 |
Nausea | 6 | 3 | 0 | 0 |
Vomiting | 1 | 1 | 0 | 0 |
Pain | ||||
Back | 1 | 1 | 0 | 0 |
Bone | 0 | 3 | 0 | 0 |
Stomach | 5 | 5 | 0 | 0 |
Tumor | 2 | 1 | 0 | 0 |
Other a | ||||
Leukocytes increased | 4 | |||
Thrombocytes increased | 3 | |||
