Table 1 Biological characterization of selected isolates
From: Isolation of more potent oncolytic paramyxovirus by bioselection
MTH87 | cl 11 | cl 15 | cl 27 | cl 29 | cl 30 | cl 37 | cl 45 | cl 48 | |
|---|---|---|---|---|---|---|---|---|---|
Syncytia formation | − | − | + | + | + | + | + | − | − |
Cytotoxicity in monolayers | ++ | + | + | + | ++ | +++ | +++ | +++ | + |
Spread of infection in monolayers (GFP) | ++ | o | ++ | o | o | + | + | ++ | + |
Cytotoxicity in spheroids | o | o | ++ | + | ++ | + | ++ | + | o |
Spread in spheroids | + | o | o | o | ++ | + | ++ | + | o |
Viral growth rate | ++ | o | ++ | + | o | + | o | ++ | + |
