Abstract
We describe a novel Minute locus, M(1)7C, on the X-chromosome of Drosophila melanogaster. Heterozygous deficient females have most, if not all, of the Minute features (short and fine bristles, rough and somewhat larger eyes, thin-textured wings, missing aristae, affected antennae, delayed development, reduced fertility, and decreased viability). Both Minute and non-Minute adult progeny from Minute mothers suffer from Minute maternal effects such as abdominal segmentation defects, fused tergites, and missing or defective legs and halteres. Using a plasmid clone from region 7C5-9, which harbours the D. melanogaster ribosomal protein gene RPS14, we have found that the accumulation of a single transcript of ∼ 650 b is extremely reduced in Minute larvae in comparison with wild-type. We have localized the RPS14 gene to ∼ 28kbp distal from the singed locus. The results suggest that M(1)1C and RPS14 may be the same gene.
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Andersson, S., Lambertsson, A. Characterization of a novel Minute-locus in Drosophila melanogaster: a putative ribosomal protein gene. Heredity 65, 51–57 (1990). https://doi.org/10.1038/hdy.1990.69
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DOI: https://doi.org/10.1038/hdy.1990.69
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