Figure 2
From: MHC genetic structure and divergence across populations of Chinook salmon (Oncorhynchus tshawytscha)
Codon-level analysis of positive selection across MHC sequences of Chinook salmon (Oncorhynchus tshawytscha). Analyses comprise the MHC class I-A1 exon (a) and MHC class II-B1 exon (b) with upper plots within each figure showing estimates of positive selection and lower plots showing the posterior probability of positive selection. Mean omegaMap estimates of positive selection (ω) are indicated by the solid black line. The dotted line in the upper plots corresponds to neutral estimates of nonsynonymous/synonymous substitutions (that is ω=1) and in the lower plots correspond to the 95% posterior probability. The grey shaded area shows the 95% CI surrounding the estimates of positive selection. Stars indicate the locations of the putative peptide-binding regions (PBR) for each molecule. Putative PBRs were identified by aligning the MHC sequences in MEGA with human HLA molecules.
