Table 1 Predicted novel exonic MEIs

From: Identification of novel exonic mobile element insertions in epithelial ovarian cancers

Chr

Insertion point

MEI

Sample

Histology

Gene

Zygosity a

PCR

Somatic/germline b

ME subfamily c

1

149939291

L1

S004

Serous

OTUD7B

Heterozygous

Yes

Germline

Undetermined

5

176918034

ALU

S011

Serous

PDLIM7

Heterozygous

Yes

Somatic

AluSx

8

55540494

ALU

S271

Serous

RP1

Heterozygous

Yes

Germline

AluS

8

71593525

ALU

S005

Serous

XKR9

Heterozygous

Yes

Germline

Undetermined

8

118183382

L1

S031

Serous

SLC30A8

Heterozygous

Yes

Somatic

L1HS

8

145694721

ALU

S117

Serous

KIFC2

Heterozygous

Yes

Germline

AluS

9

125486418

L1

S068

Serous

OR1L4

Heterozygous

No

NA

NA

14

24655945

ALU

S008

Serous

IPO4

Heterozygous

Yes

Somatic

AluSc

  1. Abbreviations: ME, mobile element; MEI, mobile element insertion; NA, not applicable.
  2. aBoth zygosity and somatic status were manually assumed using IGV and experimentally validated by PCR.
  3. bBoth zygosity and somatic status were manually assumed using IGV and experimentally validated by PCR.
  4. cMEI subfamilies were predicted using CENSOR. NA means not applicable.