Table 1 Demographic characteristics and clinical, analytic, ultrasound and structural imaging featuresa

From: Posterior paralimbic and frontal metabolite impairments in asymptomatic hypertension with different treatment outcomes

Characteristic

Non-HT

cHT

rHT

P-value

Age (years)

66.7 (5.8)

67.9 (4.3)

66.8 (5.2)

0.727

Female sex

7 (50%)

12 (70.6%)

9 (45%)

0.655

a-MMSE

28.4 (1.8)

27.6 (2.0)

27.9 (1.5)

0.514

Systolic BP (mm Hg)

138.7 (16.8)

139.8 (17.2)

149.1 (22.0)

0.268

Diastolic BP (mm Hg)

75.0 (7.8)

74.1 (7.0)

79.9 (14.8)

0.319

Disease duration (years)

—

12.2 (5.8)

10.0 (6.3)

0.297

Diabetes mellitus

2 (14.3%)

5 (29.4%)

4 (20.0%)

0.768

cardiovascular disease

1 (7.1%)

2 (11.8%)

4 (20.0%)

0.278

Tobacco

2 (14.3%)

1 (5.9%)

2 (10.0%)

0.734

Total cholesterol (mg per 100 ml)

180.5 (12.0)

182.6 (33.5)

205.5 (31.8)

0.127

HDL cholesterol (mg per 100 ml)

51.0 (4.2)

53.9 (13.0)

48.8 (10.9)

0.482

LDL cholesterol (mg per 100 ml)

101.0 (12.2)

90.9 (25.7)

123.1 (25.9)

0.008

Triglycerides (mg per 100 ml)

91.5 (31.8)

144.3 (55.6)

169.6 (67.6)

0.188

Fibrinogen (mg per 100 ml)

369.0 (17.0)

337.3 (54.1)

353.1 (70.1)

0.683

Homocysteine (μmol l−1)

8.5 (2.5)

11.0 (2.4)

10.4 (2.7)

0.449

GCA

    

 0 score

9 (64.3%)

5 (29.4%)

7 (35.0%)

0.273

 1 score

4 (28.6%)

7 (41.2%)

11 (55.0%)

 

 ⩾2 score

1 (7.1%)

5 (29.4%)

2 (10.0%)

 

Microbleeds

1 (7.1%)

3 (17.6%)

2 (10.5%)

0.831

TIS (0–3 score)

10 (71.4%)

9 (52.9%)

13 (68.4%)

0.942

FIS (0–3 score)

13 (92.9%)

15 (88.2%)

19 (100%)

0.342

IMT (mm)

 Right

0.73 (0.13)

0.74 (0.15)

0.79 (0.16)

0.387

 Left

0.74 (0.15)

0.73 (0.12)

0.77 (0.17)

0.719

Carotid plaque

 Right

4 (28.6%)

7 (43.8%)

7 (35.0%)

0.764

 Left

5 (35.7%)

4 (25.0%)

9 (45.0%)

0.511

Systolic ratio

 Right

0.77 (0.22)

0.80 (0.23)

0.84 (0.34)

0.757

 Left

0.72 (0.21)

0.71 (0.22)

0.70 (0.21)

0.979

Diastolic ratio

 Right

0.98 (0.39)

0.87 (0.27)

1.00 (0.44)

0.540

 Left

0.91 (0.29)

0.78 (0.27)

0.88 (0.31)

0.439

  1. Abbreviations: a-MMSE, adjusted mini-mental state examination; BP, blood pressure; cHT, controlled hypertension; FIS, frontal ischemic score; for ischemic burden, only the numbers and proportions for the lowest scores are displayed; GCA, global cortical atrophy; HDL, high-density lipoprotein; HT, hypertension; IMT, intima-media thickness; LDL, low-density lipoprotein; rHT, resistant hypertension; TIS, total ischemic score.
  2. aData are given as mean (s.d.) or as number (percentage).
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