Table 1 Characteristics of studied subjects

From: Pulse wave velocity in primary hyperparathyroidism and effect of surgical therapy

 

PHHT

EH

P-value

PHNT

NCS

P-value

Number of subjects (n)

28

28

—

16

18

—

Age (years)

65±10

63±10

0.410

52±14

48±15

0.431

Duration of hypertension (years)

9 (5–15)

5 (1–15)

0.454

—

—

—

BMI (kg m−2)

28.3±4.7

27.4±4.8

0.527

24.6±3.4

25.3±3.8

0.560

Plasma sodium (mmol l−1)

141±3

142±4

0.339

141±3

141±2

0.376

Plasma potassium (mmol l−1)

4.5±0.5

4.2±0.4

0.003

4.4±0.3

4.2±0.3

0.032

Plasma chloride (mmol l−1)

105±4

106±3

0.481

106±2

106±3

0.569

Plasma calcium (mmol l−1)

2.81±0.22

2.35±0.14

<0.001

2.73±0.15

2.34±0.11

<0.001

Plasma phosphorous (mmol l−1)

0.81±0.16

1.14±0.17

<0.001

0.85±0.13

1.11±0.18

<0.001

iPTH (mmol l−1)

18.1±11.5

—

—

20.2±13.8

—

—

Total plasma cholesterol (mmol l−1)

5.0±0.9

5.2±1.3

0.509

5.4±1.2

5.4±1.3

0.932

LDL cholesterol (mmol l−1)

2.9±0.9

3.0±1.1

0.756

3.7±1.0

3.3±1.2

0.398

HDL cholesterol (mmol l−1)

1.3±0.3

1.4±0.4

0.517

1.5±0.4

1.6±0.4

0.468

Triacylglycerides (mmol l−1)

1.7±1.0

1.7±0.7

0.915

1.1 (0.8–1.9)

1.0 (0.8–1.5)

0.533

Fasting plasma glucose (mmol l−1)

5.6 (4.8–6.2)

5.2 (4.4–6.0)

0.209

4.8 (4.4–5.4)

4.7 (4.6–5.4)

0.957

Creatinine (μmol l−1)

75±15

77±17

0.597

60±10

69±14

0.039

eGFR (ml min−1)

83±29

78±25

0.476

103±28

98±27

0.792

Smokers (n; %)

4 (14%)

6 (21%)

—

2 (13%)

2 (11%)

—

Clinical brachial SBP (mm Hg)

136±17

135±19

0.711

120±16

118±14

0.728

Clinical brachial DBP (mm Hg)

77±10

74±10

0.350

75±9

68±8

0.034

Brachial mean BP (mm Hg)

99±11

96±12

0.385

91±10

85±10

0.090

Brachial pulse pressure (mm Hg)

60±16

60±14

0.869

45±10

50±10

0.182

Heart rate (bpm)

70±8

70±13

0.942

72±8

66±8

0.089

Pulse wave velocity (m s−1)

10.06±2.54

8.48±2.03

0.013

7.6±1.8

5.83±0.88

<0.001

  1. Abbreviations: BMI, body mass index; eGFR, estimated glomerular filtration rate; EH, essential hypertension patients; HDL, high-density lipoprotein; iPTH; serum-intact parathyroid hormone; LDL, low-density lipoprotein; NCS, normotensive control subjects; PHHT, patients with primary hyperparathyroidism and concomitant hypertension; PHNT, primary hyperparathyroidism patients without hypertension.
  2. Values are shown as means±s.d. or medians (interquartile range) or absolute numbers and percentages. Variables are compared by unpaired t-test or Kruskal–Wallis test where appropriate.
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