Table 3 Characteristics of 15 (11 PHHT and 4 PHNT) studied subjects before and 6 months after PTX

From: Pulse wave velocity in primary hyperparathyroidism and effect of surgical therapy

 

Before

After

P-value

Age (years)

 

63±12

 

BMI (kg m−2)

27.2±4.7

27.3±4.8

0.844

Plasma sodium (mmol l−1)

141±3

141±3

0.937

Plasma potassium (mmol l−1)

4.4±0.3

4.3±0.5

0.099

Plasma chloride (mmol l−1)

106±3

104±3

0.028

Plasma calcium (mmol l−1)

2.82±0.23

2.14±0.23

<0.001

Plasma phosphorous (mmol l−1)

0.83±0.16

1.13±0.26

<0.005

iPTH (pmol l−1)

19.5±17.1

2.9±1.6

<0.005

Total plasma cholesterol (mmol l−1)

4.7±1.1

5.2±1.0

0.114

LDL cholesterol (mmol l−1)

2.9±1.0

3.1±0.9

0.432

HDL cholesterol (mmol l−1)

1.3±0.4

1.3±0.3

0.908

Triacylglycerides (mmol l−1)

1.2 (1.0-1.9)

1.2 (0.9-1.5)

0.859

Fasting plasma glucose (mmol l−1)

5.2±0.9

5.7±1.5

0.246

Creatinine (μmol l−1)

68±12

76±18

0.054

eGFR (ml min−1)

89±32

83±33

0.065

Clinical brachial SBP (mm Hg)

131±20

123±18

0.004

Clinical brachial DBP (mm Hg)

75±13

75±11

0.922

Brachial mean BP (mm Hg)

94±14

91±12

0.276

Brachial pulse pressure (mm Hg)

56±13

48±12

0.001

Heart rate (bpm)

69±9

68±10

0.659

Pulse wave velocity (m s−1)

9.05±1.81

8.54±1.79

0.024

  1. Abbreviations: BMI, body mass index; BP, blood pressure; DBP, diastolic blood pressure; eGFR, estimated glomerular filtration rate; HDL, high-density lipoprotein; iPTH; serum-intact parathyroid hormone; LDL, low-density lipoprotein; PHHT, patients with primary hyperparathyroidism and concomitant hypertension; PHNT, primary hyperparathyroidism patients without hypertension; PTX, parathyroidectomy; SBP, systolic blood pressure.
  2. Values are shown as means±s.d. or medians (interquartile range). Variables are compared by paired t-test or Wilcoxon's pair test where appropriate.