Table 1 Effect of THC on hemodynamic status of rats in all experimental groups
Group | SBP (mm Hg) | DBP (mm Hg) | MAP (mm Hg) | HR (beats per min) | HBF (ml min −1 per 100 g tissue) | HVR (mm Hg min per 100 g tissue per ml) |
|---|---|---|---|---|---|---|
Normotensive | ||||||
Vehicle | 129.7±5.3 | 89.3±3.6 | 101.8±2.7 | 304.9±15.3 | 8.6±0.9 | 12.5±0.9 |
THC 50 mg kg−1 per day | 126.2±2.4 | 77.6±3.2 | 98.5±3.0 | 308.4±16.0 | 8.9±0.8 | 11.8±1.1 |
THC 100 mg kg−1 per day | 124.9±3.6 | 79.7±3.9 | 97.8±2.8 | 324.3±17.6 | 8.9±0.6 | 11.4±1.0 |
L-NAME-induced hypertension | ||||||
Vehicle | 218.7±3.3* | 167.0±1.5* | 189.8±1.9* | 338.2±12.0 | 2.7±0.5* | 83.2±11.2* |
THC 50 mg kg−1 per day | 204.0±4.0*,† | 145.8±4.0*,† | 174.1±1.7*,† | 333.6±9.8 | 3.4±0.4* | 55.2±8.4*,† |
THC 100 mg kg−1 per day | 194.3±1.6*,† | 145.2±1.5*,† | 165.5±1.8*,†,‡ | 303.3±14.3 | 3.4±0.5* | 52.2±7.8*,† |
