Figure 1 | Hypertension Research

Figure 1

From: Coupling factor 6 enhances the spontaneous microaggregation of platelets by decreasing cytosolic cAMP irrespective of antiplatelet therapy

Figure 1

(A) Representative tracings of flow cytometry for platelet surface associated α- and β-subunits of ATP synthase before and after preincubating with CF6 at 10-7 M. (B) The α- and β-subunits of ATP synthase were measured by western blot analysis. GAPDH; glyceraldehyde-3-phosphate dehydrogenase. (C) Effect of CF6 on intracellular pH. (a) Intracellular pH after administration of CF6 at 10-7 M. (b) Effect of pretreatment with efrapeptin (EF) at 10-5 M on intracellular pH in response to CF6 at 10-7 M.

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