Table 5 Cox regression analysis for cardiovascular mortality in patients with dialysis
Simple regression | Multiple regression | |||
|---|---|---|---|---|
P-value | Odds ratio | P-value | Odds ratio | |
Age, 10 year | 0.73 | 1.16 (0.51–2.64) | ||
Male gender | 0.32 | 1.87 (0.55–6.40) | ||
Body surface area, m2 | 0.46 | 0.15 (0.01–24.3) | ||
Dialysis vintage, years | 0.07 | 1.09 (0.99–1.20) | 0.88 | |
Intradialytic HTN | 0.09 | 2.79 (0.84–9.11) | 0.76 | |
Filtration volume/hour, kg h−1 | 0.89 | 1.00 (0.99–1.00) | ||
Interdialytic weight gain, kg | 0.87 | 0.95 (0.50–1.78) | ||
Kt/v | 0.43 | 1.50 (0.55–4.10) | ||
Cardiothoracic ratio, % | 0.27 | 1.08 (0.94–1.24) | ||
Supine SBP pre, mm Hg | 0.88 | 1.00 (0.98–1.03) | ||
Supine SBP post, mm Hg | 0.06 | 1.02 (0.99–1.05) | 0.26 | |
Echocardiographic variables | ||||
Baseline LVDD pre, mm | 0.11 | 1.08 (0.98–1.20) | ||
Baseline LVEF, % | 0.57 | 0.17 (0.01–80.1) | ||
Baseline E wave, cm s−1 | 0.74 | 1.00 (0.97–1.03) | ||
Baseline mitral E/A ratio | 0.65 | 0.55 (0.04–7.30) | ||
Baseline E′, cm s−1 | 0.63 | 0.87 (0.49–1.54) | ||
Baseline E/E′ | 0.96 | 1.00 (0.92–1.09) | ||
ΔLVDD (pre-post), cm s−1 | 0.89 | 0.99 (0.88–1.12) | ||
ΔLVEF (pre-post), % | 0.74 | 2.20 (0.02–215.9) | ||
ΔE wave (pre-post), cm s−1 | 0.27 | 1.02 (0.98–1.06) | ||
ΔMitral E/A (pre-post) | 0.65 | 2.04 (0.10–43.5) | ||
ΔE′ (pre-post), cm s−1 | 0.33 | 0.77 (0.46–1.31) | ||
ΔE/E′ (pre-post) | 0.12 | 0.92 (0.83–1.02) | ||
Laboratory data | ||||
Serum albumin, g dl−1 | 0.04 | 14.9 (1.10–200.3) | 0.07 | |
Total cholesterol, mg dl−1 | 0.30 | 1.01 (0.99–1.03) | ||
Serum calcium, mg dl−1 | 0.17 | 1.53 (0.83–2.81) | ||
Serum phosphate, mg dl−1 | 0.62 | 0.88 (0.54–1.45) | ||
Serum ALT, U l−1 | 0.38 | 1.03 (0.96–1.11) | ||
Serum sodium, mEq l−1 | 0.81 | 1.02 (0.85–1.24) | ||
Serum potassium, mEq l−1 | 0.04 | 0.41 (0.18–0.97) | 0.01 | 0.31 (0.12–0.77) |
Hemoglobin, g dl−1 | 0.82 | 1.06 (0.65–1.72) | ||
White blood cells, 103 μl−1 | 0.02 | 0.94 (0.89–0.99) | 0.06 | |
Platelet count, 109 l−1 | 0.21 | 0.94 (0.84–1.04) | ||
Blood glucose, mg dl−1 | 0.60 | 1.00 (0.98–1.01) | ||
Comorbidities, n (%) | ||||
Diabetes mellitus | 0.02 | 9.97 (1.57–63.4) | 0.06 | |
Hypertension | 0.86 | 0.83 (0.54–6.39) | ||
Dyslipidemia | 0.03 | 5.62 (1.17–27.1) | 0.053 | |
Coronary artery disease | 0.07 | 3.29 (0.90–12.0) | 0.04 | 4.86 (1.05–22.4) |
Medication, n (%) | ||||
ARB/ACE-inhibitors | 0.11 | 7.12 (0.65–78.5) | ||
Calcium channel blockers | 0.32 | 2.03 (0.50–8.16) | ||
Beta-blockers | 0.89 | 0.89 (0.18–4.37) | ||
