Table 1 Body weight, food intake and urine output in DSS rats

From: Effect of dipeptidyl peptidase-4 inhibition on circadian blood pressure during the development of salt-dependent hypertension in rats

 

Baseline (NS diet)

7 Days HS-diet feeding

7 Days NS-diet feeding

Group

Bwt (g)

Food intake (g per day)

Urine volume (ml per day)

Bwt (g)

Food intake (g per day)

Urine volume (ml per day)

Bwt (g)

Food intake (g per day)

Urine volume (ml per day)

DSS/NS+vehicle

254±8

24.3±2.2

8.4±0.2

288±4

22.0±0.5

8.2±1.0

326±6

23.0 ±0.5

10.3±0.6

DSS/HS+vehicle

257±4

21.7±0.3

7.2±0.7

287±5

21.5±1.0

57.3±2.8***, ‖‖‖

324±2

21.7±0.4

12.9±1.6###

DSS/HS+vildagliptin-low dose

262±4

19.1±1.2

8.7±0.6

291±4

22.0±0.6

62.7±2.5‖‖‖

332±2

21.0±0.4

10.5±0.6###

DSS/HS+vildagliptin-high dose

255±5

20.0±0.4

8.8±1.5

282±4

20.7±0.9

65.6±0.9†, ‖‖‖

315±4

20.0±0.4

12.93±1.6###

  1. Abbreviations: Bwt, body weight; DSS, Dahl salt-sensitive; HS, high-salt diet (8% NaCl); NS, normal salt diet (0.3% NaCl). ***P<0.005 NS+vehicle versus HS+vehicle; †P<0.05 HS+vehicle versus vildagliptin-high dose; ‖‖‖P<0.005 versus baseline in each group; ###P<0.005 versus 7 days after HS diet in each group.
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