Figure 3 | Hypertension Research

Figure 3

From: Coupling factor 6 attenuates CXCR4 expression through the HIF-1α and c-Src pathways and promotes endothelial apoptosis and inflammation

Figure 3

Flow cytometric analysis of apoptosis with annexin-V-FITC and propidium iodide (PI) label in human umbilical vein endothelial cells (HUVECs). (a) Representative charts under normoxia and hypoxia for 24 h with or without CF6 at 10−7 M and a 40-h pretreatment with HIF-1α small interfering RNA (siRNA) at 100 nM. P<0.05 vs. control (n=3). (b) Representative charts under normoxia and hypoxia for 24 h with or without CF6 and stromal-derived factor-1α (SDF-1α) at 300 ng ml−1. P<0.05 vs. control (n=3). A full color version of this figure is available at the Hypertension Research journal online.

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