Table 1 Baseline data and drug administration following acquisition of baseline dataa

From: Seeking a blood pressure-independent measure of vascular properties

Parameter

Fisher young (n=8)

Fisher old (n=7)

Pb

SHR young (n=5)

SHR old (n=6)

Pb

Baseline values

 SBP (mm Hg)

124.3 (15.7)

125.7 (21.5)

0.91

124.1 (45.2)

171.5 (12.7)

0.035*

 MAP (mm Hg)

88.5 (11.0)

87.2 (14.9)

0.85

82.5 (31.5)

123.3 (11.1)

0.015*

 DBP (mm Hg)

87.0 (10.9)

84.0 (14.6)

0.67

79.8 (31.6)

120.9 (11.2)

0.015*

 HR (mm Hg)

320.1 (21.9)

272.9 (35.1)

0.007*

353.7 (58.6)

356.2 (46.7)

0.94

 PP (mm Hg)

37.4 (5.3)

41.3 (7.4)

0.25

44.2 (15.1)

50.6 (4.1)

0.35

 PWV (m s−1)

3.69 (0.28)

4.12 (0.79)

0.17

4.12 (0.06)

5.87 (0.85)

0.004*

DBP (mm Hg) at

 Onset of measurements

135.6 (2.2)

140.3 (3.9)

0.57

148.5 (19.1)

147.3 (6.61)

0.89

 Middle of measurement

115.0 (5.2)

104.8 (13.9)

0.07

113.2 (26.6)

121.0 (12.1)

0.54

 Last measurement

77.2 (7.2)

68.3 (17.2)

0.20

61.5 (9.5)

95.2 (19.4)

<0.0001*

Total phenylephrine dose (mcg)

14.7 (3.7)

38.2 (25.5)

0.022*

9.2 (3.2)

7.6 (4.5)

0.52

  1. Abbreviations: DBP, diastolic blood pressure; HR, heart rate; MAP, mean arterial pressure; PP, pulse pressure; PWV, pulse wave velocity; SBP, systolic blood pressure; SHR, spontaneously hypertensive rats.
  2. aAll values given as mean (s.d.).
  3. bAs determined by Student’s t-test.*Denotes significance below 0.05.