Figure 3 | Hypertension Research

Figure 3

From: Endothelial function does not improve with high-intensity continuous exercise training in SHR: implications of eNOS uncoupling

Figure 3

High-intensity exercise decreases eNOS-dependent vasorelaxation in SHR. (a) Dose-dependent response to a cumulative dose of ACh in aortic rings pretreated with indomethacin+TRAM 34+apamin. The data are expressed as the percentage of relaxation relative to the preconstriction level. (b) ACh concentration inducing 50% of the maximal response to ACh in aortic rings pretreated with indomethacin+TRAM 34+apamin. (c) Maximal relaxation in response to ACh of aortic rings pretreated with indomethacin+TRAM 34+apamin and expressed as the percentage of relaxation relative to the preconstriction level. The values are the mean±s.e.m. *P<0.05 vs. WKY group. †P<0.05 vs. SHR group.

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