Table 3 Incidence of primary and secondary endpoints

From: Effects of calcium channel blocker benidipine-based combination therapy on target blood pressure control and cardiovascular outcome: a sub-analysis of the COPE trial

 

Good control (n=1733)

Poor control (n=1268)

P-value (log-rank)

Primary endpoints

 Composite cardiovascular events

53 (8.2)

56 (12.1)

0.041

Secondary endpoints

 Hard composite cardiovascular events

27 (4.1)

33 (7.1)

0.038

 Fatal and non-fatal stroke including TIA

21 (3.2)

27 (5.8)

0.042

 Cardiac events

24 (3.7)

25 (5.3)

0.196

 All-cause mortality

33 (5.0)

28 (5.9)

0.474

 New-onset diabetes

56 (8.7)

34 (7.3)

0.397

  1. Abbreviation: TIA, transient ischemic attack.
  2. Hard composite cardiovascular events were consist of cardiovascular death, non-fatal myocardial infarction and non-fatal stroke. Differences in the primary and secondary events between the good control group and the poor control group were analyzed using Tukey’s multiple comparison test. Data are shown as incidence number (per 1000 patients years).
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