Table 1A Comparison of baseline characteristics of patients with and without diabetes mellitus (DM)

From: Increased cardiovascular risk of treated white coat and masked hypertension in patients with diabetes and chronic kidney disease: the HONEST Study

 

All (n=21591)

DM patients (n=4426)

Non-DM patients (n=17165)

Pa (non-DM vs. DM)

Male, n (%)

10 670 (49.4)

2474 (55.9)

8196 (47.7)

<0.0001

Age, years

64.9±11.9

66.1±10.8

64.5±12.1

<0.0001

Body mass index, kg m−2

24.3±3.7

25.2±4.0

24.0±3.5

<0.0001

Duration of hypertension, years

5.0±4.4

6.2±4.4

4.7±4.4

<0.0001

History of cerebro- or cardiovascular disease, n (%)

2269 (10.5)

655 (14.8)

1614 (9.4)

<0.0001

 Cerebrovascular disease, n (%)

1432 (6.6)

377 (8.5)

1055 (6.1)

<0.0001

 Cardiovascular disease, n (%)

981 (4.5)

330 (7.5)

651 (3.8)

<0.0001

Complications

 Dyslipidemia, n (%)

9626 (44.6)

2825 (63.8)

6801 (39.6)

<0.0001

 Chronic kidney disease, n (%)

4346 (20.1)

1245 (28.1)

3101 (18.1)

<0.0001

Current smokers, n (%)

2654 (12.3)

595 (13.4)

2059 (12.0)

<0.0001

Regular alcohol drinkers, n (%)

3473 (16.1)

703 (15.9)

2770 (16.1)

0.32

Previous antihypertensive drug use, n (%)

10 872 (50.4)

2805 (63.4)

8067 (47.0)

<0.0001

 Calcium channel blocker

7783 (36.0)

1995 (45.1)

5788 (33.7)

<0.0001

 Angiotensin receptor blocker

4581 (21.2)

1401 (31.7)

3180 (18.5)

<0.0001

 β-Blocker

1380 (6.4)

341 (7.7)

1039 (6.1)

<0.0001

 Diuretic

1260 (5.8)

381 (8.6)

879 (5.1)

<0.0001

 Angiotensin-converting enzyme inhibitor

785 (3.6)

273 (6.2)

512 (3.0)

<0.0001

 α-Blocker

470 (2.2)

160 (3.6)

310 (1.8)

<0.0001

 Other antihypertensive drugs

97 (0.4)

35 (0.8)

62 (0.4)

0.0001

Clinic measurements

 Systolic BP, mm Hg

153.6±19.0

151.2±18.3

154.2±19.1

<0.0001

 Diastolic BP, mm Hg

87.1±13.3

83.1±13.0

88.2±13.2

<0.0001

 Pulse rate, beats per min

74.0±11.2

74.8±11.5

73.8±11.1

<0.0001

Home measurements (morning)

 Systolic BP, mm Hg

151.2±16.3

148.9±16.1

151.8±16.3

<0.0001

 Diastolic BP, mm Hg

86.9±11.7

82.9±11.5

88.0±11.5

<0.0001

 Pulse rate, beats per min

70.7±9.8

71.0±10.3

70.7±9.7

0.18

Fasting plasma glucose, mg dl−1

106.0±29.8

136.0±46.6

97.6±14.5

<0.0001

HbA1c, % (NGSP)

6.19±1.09

7.16±1.22

5.64±0.44

<0.0001

eGFR, ml min−1 per 1.73 m2

72.4±20.2

71.6±21.9

72.6±19.7

0.008

  1. Abbreviations: BP, blood pressure; eGFR, estimated glomerular filtration rate; HbA1c, glycated hemoglobin A1c; NGSP, National Glycohemoglobin Standardization Program.
  2. aCategorical data analyzed by χ2 test and quantitative data by unpaired t-test.