Table 1 Patient characteristics

From: The effects of increasing calcium channel blocker dose vs. adding a diuretic to treatment regimens for patients with uncontrolled hypertension

 

HD group (n=62)

D group (n=63)

P

Women, n (%)

15 (24.2)

19 (30.2)

0.45

Age (years)

64.9±12.1

67.1±14.2

0.36

Body mass index (kg m−2)

24.6±3.6

24.7±2.9

0.83

Diabetes mellitus, n (%)

18 (29.0)

14 (22.2)

0.38

Dyslipidemia, n (%)

20 (32.3)

22 (34.9)

0.75

Chronic kidney disease, n (%)

21 (33.9)

20 (31.8)

0.80

eGFR (ml min−1 per 1.73 m2)

71.8±16.2

68.5±17.1

0.26

Coronary artery disease, n (%)

8 (12.9)

13 (20.6)

0.25

Stroke, n (%)

3 (4.8)

4 (6.3)

0.71

Chronic heart failure, n (%)

5 (8.1)

8 (17.1)

0.40

Clinic systolic blood pressure

137.1 (15.3)

136.7 (15.4)

0.88

Clinic diastolic blood pressure

77.2 (11.9)

77.1 (11.9)

0.94

Clinic heart rate

71.9 (11.9)

72.7 (9.0)

0.70

  1. Abbreviation: eGFR, estimated glomerular filtration rate.
  2. Data are shown as the number (percent) of patients or arithmetic mean±s.d. After the randomization, patients allocated to HD group took the combination of 100 mg per day of irbesartan and 10 mg of amlodipine, and those allocated to D group took the combination of 100 mg per day irbesartan and 5 mg per day of amlodipine and 1 mg of indapamide.
  3. P denotes the significance of difference between HD and D groups.
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