Figure 1
From: Maternal high-fat diet impacts endothelial function in nonhuman primate offspring
ACh-induced endothelium-dependent vasorelaxation response in abdominal aorta tissue. (a) Cumulative concentration-relaxation (%) curves for ACh (−10 to −5.5 LogM) in abdominal aorta rings against U46619 (9,11-dideoxy-11α, 9α-epoxy-methanoprostaglandin F2α). (b) Corresponding EC50 value for each curve. (c) Correlative relationship between EC50 and IAUC for juveniles born to HFD consumption dams. (d) Contracting forces against U46619. Values were expressed as mean±s.e., n=6–10. **P<0.01 vs C/C, ΔP<0.05 and ΔΔP<0.01 vs H/H.
