Table 1 Demographic and clinical characteristics of patients

From: Addiction potential of phentermine prescribed during long-term treatment of obesity

 

APT (N=152)

LPT (N=117)

Significant difference a

Asked, consented, completed, (LTP) withdrawal completed

158, 152, 152

124, 117, 117, 76

 
 

Mean (s.d.)

Mean (s.d.)

 

Age

44.18 (12.39)

51.18 (11.40)

t=−4.757, df=267, P<0.001

BMI

34.88 (7.31)

33.79 (7.59)

t=1.198, df=267, P=0.232

Days of phentermine treatment

9.30 (3.35)

  

Years of phentermine treatment

 

8.35 (5.16)

 

Rx Duration, Range (days/years)

4–22

1.1–21.5

 

Phentermine-HCl (mg)

34.46 (9.23)

53.43 (19.46)

t=−9.732, df=267, P<0.001

Phentermine dose range (mg/d)

15–93.75

18.75–112.5

 

Number of office examinations

 

72.1 (51.7)

 

Patients who had taken treatment hiatus<1 month

 

117 (100%)

 

Patients who had taken treatment hiatus>1 month

 

70 (60%)

 

Average treatment hiatus (mo)

 

19.5 (19.9)

 
 

N (%)

N (%)

 

Sex (female)

134 (88.2)

108 (92.3)

χ2=1.261, df=1, P=0.261

Race

 White

138 (90.8)

103 (88.0)

χ2=1.812, df=3, P=0.612

 Hispanic

10 (6.6)

(7.7)

 

 Black

1 (0.7)

(2.6)

 

 Asia

3 (2.0)

2 (1.7)

 

Concomitant antidepressant

2 (1.3)

24 (20.5)

 

 Bupropion

 

3

 

 Citalopram

 

5

 

 Desvenlafaxine

 

1

 

 Duloxetine

1

  

 Escitalopram

 

5

 

 Fluoxetine

 

4

 

 Paroxetine

 

1

 

 Sertraline

 

2

 

 Trazodone

 

3

 

 Venlafaxine

1

  

Other antiobesity medications

0

6 (5.1)

 

 Topiramate

 

4

 

 Diethylpropion

 

2

 
  1. LPT patients were older and received higher doses of phentermine.
  2. aOnly the differences of age, BMI, phentermine dose, sex and race between groups were compared.