Figure 2 | International Journal of Obesity

Figure 2

From: Sympathetic hyper-excitation in obesity and pulmonary hypertension: physiological relevance to the ‘obesity paradox’

Figure 2

(a) Typical microangiogram images showing the branching pattern of small pulmonary arteries in an obese normoxic rat. (b) The number of opaque vessels (mean±s.e.m.), and (c) the range of vessel sizes (box and whisker graph) at each of the first four branching generations of the pulmonary circulation, in lean and obese rats exposed to normoxia (lean-N, n=7; obese-N, n=7), or chronic hypoxia (lean-CH, n=7; obese-CH, n=7) for 2 weeks. (d) Microangiograms illustrating vasoconstriction of pulmonary vessels (black arrows) in response to acute hypoxia (8% O2 for 5 min) in an obese normoxic rat. Severe vasoconstriction in some vessels prevented the entry of contrast medium into the vessel, as highlighted by the red box. The tungsten wire in the bottom right corner of each angiograpm is a reference of 50 μm diameter. A full color version of this figure is available at the International Journal of Obesity journal online.

Back to article page