Table 3 Measures of fat distribution and lean body mass association with impaired fasting glucose, hypertriglyceridemia, hypertension and insulin resistance in men and women

From: Comparison of regional fat measurements by dual-energy X-ray absorptiometry and conventional anthropometry and their association with markers of diabetes and cardiovascular disease risk

 

Z-Waist OR (95% CI)

Z-Android fat OR (95% CI)

Z-Visceral fat OR (95% CI)

Z- abdominal SAT OR (95% CI)

Z-arm fat OR (95% CI)

Z-Hip OR (95% CI)

Z-Gynoid fat OR (95% CI)

Z-Leg fat OR (95% CI)

Z-lean body mass OR (95% CI)

MODEL 1

 Men (n=2119)

Impaired fasting glucose (n=626)

1.62 (1.46, 1.80)

1.71 (1.53, 1.90)

1.79 (1.60, 2.01)

1.39 (1.26, 1.55)

1.41 (1.28, 1.56)

1.39 (1.26, 1.54)

1.51 (1.36, 1.68)

1.37 (1.24, 1.52)

1.18 (1.06, 1.31)

Hypertriglyceridemia (n=661)

2.48 (2.20, 2.79)

2.78 (2.45, 3.15)

3.27 (2.85, 3.76)

1.69 (1.51, 1.87)

2.10 (1.87, 2.34)

1.81 (1.63, 2.02)

1.95 (1.74, 2.17)

1.66 (1.49, 1.84)

1.32 (1.18, 1.46)

Hypertension (n=377)

1.88 (1.66, 2.14)

1.95 (1.70, 2.23)

2.17 (1.89, 2.50)

1.41 (1.24, 1.59)

1.56 (1.37, 1.76)

1.55 (1.37, 1.75)

1.51 (1.33, 1.72)

1.36 (1.20, 1.53)

1.16 (1.02, 1.31)

Insulin resistance (n=647)

2.74 (2.41, 3.10)

3.68 (3.21, 4.23)

3.16 (2.74, 3.62)

2.01 (1.80, 2.26)

2.11 (1.88, 2.36)

1.92 (1.72, 2.14)

2.21 (1.97, 2.49)

1.86 (1.67, 2.09)

1.39 (1.24, 1.54)

 Women (n=2831)

Impaired fasting glucose (n=285)

2.21 (1.90, 2.53)

2.33 (2.01, 2.69)

2.58 (2.21, 3.01)

1.98 (1.72, 2.28)

1.94 (1.69, 2.23)

1.89 (1.65, 2.17)

1.82 (1.58, 2.08)

1.59 (1.39, 1.82)

1.32 (1.14, 1.53)

Hypertriglyceridemia (n=281)

2.68 (2.31, 3.11)

2.91 (2.49, 3.39)

3.44 (2.92, 4.06)

2.32 (2.01, 2.68)

2.34 (2.02, 2.71)

1.91 (1.67, 2.19)

1.83 (1.59, 2.09)

1.63 (1.43, 1.86)

1.33 (1.15, 1.54)

Hypertension (n=194)

1.95 (1.66, 2.29)

1.96 (1.67, 2.32)

2.18 (1.84, 2.58)

1.71 (1.45, 2.01)

1.73 (1.47, 2.02)

1.64 (1.40, 1.92)

1.48 (1.27, 1.73)

1.33 (1.13, 1.54)

1.03 (0.86, 1.22)

Insulin resistance (n=505)

3.43 (3.00, 3.92)

3.03 (2.64, 3.46)

4.03 (3.48, 4.66)

2.99 (2.63, 3.39)

2.95 (2.60, 3.35)

2.56 (2.27, 2.89)

2.45 (2.18, 2.76)

2.06 (1.83, 2.30)

1.37 (1.22, 1.54)

MODEL 2

 Men (n=2119)

Impaired fasting glucose (n=626)

1.07 (0.86, 1.34)

1.93 (1.30, 2.88)

1.69 (1.36, 2.11)

0.73 (0.61, 0.87)

0.56 (0.43, 0.72)

0.82 (0.69, 1.02)

0.79 (0.61, 1.03)

0.61 (0.49, 0.76)

1.07 (0.95, 1.20)

Hypertriglyceridemia (n=661)

1.83 (1.45, 2.32)

5.01 (3.25, 7.69)

3.64 (2.82, 4.70)

0.56 (0.47, 0.67)

0.73 (0.57, 0.96)

0.89 (0.75, 1.06)

0.44 (0.34, 0.58)

0.32 (0.25, 0.41)

1.10 (0.98, 1.25)

Hypertension (n=377)

1.16 (0.88, 1.53)

2.65 (1.63, 4.31)

2.49 (1.88, 3.31)

0.55 (0.45, 0.67)

0.58 (0.43, 0.79)

0.91 (0.75, 1.11)

0.44 (0.32, 0.61)

0.38 (0.29, 0.50)

0.97 (0.84, 1.13)

Insulin resistance (n=647)

1.54 (1.21, 1.98)

3.89 (2.51, 6.02)

2.36 (1.83, 3.02)

0.70 (0.57, 0.84)

0.48 (0.36, 0.63)

0.80 (0.67, 0.96)

0.57 (0.42, 0.75)

0.39 (0.31, 0.50)

1.14 (0.92, 1.29)

 Women (n=2831)

Impaired fasting glucose (n=285)

1.40 (1.06, 1.85)

2.69 (1.67, 4.34)

2.39 (1.83, 3.13)

0.59 (0.41, 0.87)

0.76 (0.55, 1.06)

0.81 (0.62, 1.05)

0.57 (0.42, 0.78)

0.50 (0.38, 0.64)

1.07 (0.91, 1.28)

Hypertriglyceridemia (n=281)

1.63 (1.23, 2.18)

4.15 (2.52, 6.82)

3.57 (2.67, 4.78)

0.63 (0.43, 0.93)

0.88 (0.63, 1.23)

0.48 (0.38, 0.63)

0.25 (0.18, 0.35)

0.30 (0.23, 0.40)

1.09 (0.91, 1.31)

Hypertension (n=194)

1.41 (1.02, 1.94)

2.38 (1.37, 4.16)

2.22 (1.63, 3.02)

0.61 (0.38, 0.93)

0.87 (0.59, 1.29)

0.84 (0.62, 1.15)

0.41 (0.28, 0.58)

0.41 (0.31, 0.55)

0.88 (0.72, 1.08)

Insulin resistance (n=505)

1.75 (1.38, 2.23)

3.43 (2.27, 5.18)

2.84 (2.24, 3.60)

0.82 (0.59, 1.13)

0.95 (0.71, 1.26)

0.69 (0.56, 0.86)

0.43 (0.33, 0.56)

0.36 (0.29, 0.45)

1.13 (0.98, 1.31)

  1. Estimates presented as odds ratios (OR) and 95% confidence interval (CI) and represent risk of outcome with 1 s.d. increase in adiposity measurement. †Model 1: adjusted for age, smoking, physical activity, alcohol intake. ‡Model 2: adjusted for age, smoking, physical activity, alcohol intake and BMI for waist and hip circumferences/FMI for DXA-derived depots.
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