Table 3 Comparison of histopathological diagnosis and detection accuracy between objective AVM and IOM

From: Detection accuracy for epithelial dysplasia using an objective autofluorescence visualization method based on the luminance ratio

Items

Histopathological diagnosis epithelial dysplasia

Total

Kappa statistics (95% confident interval)

 

Positive

Negative

  

Subjective AVM

 FVL-positive

55

11

66

0.132

 FVL-negative

9

4

13

(−0.196–0.461)

IOM

 Iodine-unstained area

61

13

74

0.116

 Iodine-stained area

3

2

5

(−0.271–0.503)

Objective AVM

 FVL-positive

58

3

61

0.656

 FVL-negative

6

12

18

(0.444–0.868)

 

Sensitivity

Specificity

Positive predictive value

Negative predictive value

Accuracy

Positive likelihood ratio

Negative likelihood ratio

Subjective AVM

85.9%

26.7%

83.3%

30.8%

74.7%

1.17

0.53

IOM

95.3%

13.3%

82.4%

40.0%

79.7%

1.10

0.35

Objective AVM

90.6%

80.0%

95.1%

66.7%

88.6%

0.12

  1. AVM, autofluorescence visualization method; FVL, fluorescence visualization loss; IOM, iodine-staining method.