Abstract
In our screening program for new antifungal agents from microbial secondary metabolites, two new isoflavonol glycosides with potent antifungal activity, talosins A and B, were isolated from the culture broth of Kitasatospora kifunensis MJM341. Talosins A and B were determined to be genistein 7-α-L-6-deoxy-talopyranoside and genistein 4′,7-di-α-L-6-deoxy-talopyranoside, respectively, by spectroscopic studies. They are the first flavonoid glycosides incorporating 6-deoxy-talose as a sugar component.
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References
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Kim, WG., Yoon, T., Kwon, H. et al. Talosins A and B: New Isoflavonol Glycosides with Potent Antifungal Activity from Kitasatospora kifunensis MJM341. J Antibiot 59, 640–645 (2006). https://doi.org/10.1038/ja.2006.85
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DOI: https://doi.org/10.1038/ja.2006.85
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