Table 3 False positive rates (FPRs)a applying New Jersey-recommended critical congenital heart defects (CCHD) screening algorithm, b

From: Evaluation of critical congenital heart defects screening using pulse oximetry in the neonatal intensive care unit

 

Overall FPR

FPR among infants without a prenatal CHD diagnosis or echocardiogram before screen

 

% (95% CI)

% (95% CI)

FPR for CCHD

 Overall

0.8 (0.6, 1.1)

0.6 (0.4, 0.9)

 Stage 1

On oxygen

2.1 (1.2, 3.7)

1.6 (0.8, 3.3)

No oxygen

0.5 (0.3, 0.9)

0.6 (0.4, 0.9)

Extremely premature (<28 weeks)

3.8 (1.4, 10.2)

4.0 (1.5, 10.8)

 Stage 2

0.6 (0.3, 1.4)

0.3 (0.1, 1.1)

FPR for CCHD+noncritical CHD

 Overall

0.7 (0.5, 1.0)

0.6 (0.4, 0.9)

 Stage 1

On oxygen

2.1 (1.1, 3.7)

1.7 (0.9, 3.5)

No oxygen

0.5 (0.3, 0.9)

0.6 (0.4, 0.9)

Extremely premature (<28 weeks)

4.0 (1.5, 10.6)

4.2 (1.6, 11.2)

 Stage 2

0.4 (0.1, 1.2)

0.3 (0.1, 1.2)

  1. Abbreviations: CHD, congenital heart defects; CI, confidence interval.
  2. aFail/rescreen=<95% either or >3%.
  3. bConditional passes are considered passes in all FPR calculations.