Figure 5
From: Intraocular expression and release of high-mobility group box 1 protein in retinal detachment
RPE cells migrate in response to HMGB1. Representative photographs of ARPE-19 cells stained with Diff-Quick after migration toward control medium (a) or 100 ng/ml HMGB1 (b). Original magnification: × 100. (c) HMGB1 stimulated ARPE-19 cell migration in a concentration-dependent manner with a 2.7-fold maximal response at 100 ng/ml. The data represent the mean±s.d. (n=3). All treatments increase the migratory response relative to the control (P<0.01 in Student's t-test). Similar results were obtained from three independent experiments.
