Figure 5
From: The fibromatosis signature defines a robust stromal response in breast carcinoma
Network properties of the DTF core and DTF non-core protein–protein interaction networks. Each node represents a protein and the links between nodes represent known or predicted functional protein–protein interactions. The degree of a node indicates its number of links to other nodes. The network is visualized using the Cytoscape software platform for visualizing molecular interaction networks with the Cytoscape spring-embedded layout. Only proteins with at least three links to other proteins in the network are displayed. The size of the node correlates with the number of links it has with other proteins. Cytoscape plug-in Network Analyzer 2.5 was used to compute the degree distributions of the two networks. (a) The DTF non-core protein–protein interaction network (left, in gray). (b) The DTF core protein–protein interaction network (right, in red). (c) Histogram of the distribution of links per node in the DTF non-core protein–protein interaction network (gray) and the DTF core protein–protein interaction network (red).
