Table 2 Relationship between seladin-1/DHCR24 expression and clinical features of patients treated by radical prostatectomy

From: Androgen receptor regulation of the seladin-1/DHCR24 gene: altered expression in prostate cancer

Clinical features

Patients treated by surgery (n=61)

PSA recurrence

n=58

 No

160.8

 Yes

282.5

 

P=0.73

Stage

n=61

 pT2

65.8

 pT3-T4

239.3

 

P =0.04

Lymph node

n=61

 No

168

 Yes

230

 

P=0.6

Surgical margin

n=34

 No

169

 Yes

1217.5

 

P=0.07

Bladder invasion

n=34

 No

170

 Yes

2691

 

P =0.006

Gleason score

n=61

 <7

170

 7

92.5

 >7

28.2

 

P=0.31

PSA at diagnosis

n=38

 <9

207.5

 ⩾9

239.3

 

P=0.68

  1. PSA, prostate-specific antigen.
  2. The numbers indicate seladin-1/DHCR24 expression (fg mRNA/μg total RNA, median value). Statistical analysis was performed by Mann–Whitney test and Wilcoxon's rank sum test; n represents the number of CaP patients falling into the indicated clinical features category. Significant values (P<0.05) are in bold font.
Back to article page