Figure 5

IL-1F6 protein and Il1f6 mRNA expressions in the kidneys of various renal disease model mice. (a, c) The number of IL-1F6-positive tubules in the kidneys of C57BL/6 (control), lupus models (BXSB, NZB/WF1, MRL/lpr), and NS model (ICGN) mice in the early (a) and late stages of the disease (c). (b, d) Levels of Il1f6 mRNA expressions in the kidneys of mice in the early (b) and late stages of the disease (d). Each value is expressed as mean (s.e.); *: significantly different from the C57BL/6 mice in each stage of the disease (Mann–Whitney U-test, P<0.05); n=3.