Table 2 Echocardiography measurements

From: Cardiac hypertrophy in mice with long-chain acyl-CoA dehydrogenase or very long-chain acyl-CoA dehydrogenase deficiency

Parameter

WT

LCAD−/−

P

LVID;d (mm)

3.53±0.08

3.73±0.1

>0.05

LVID;s (mm)

2.24±0.09

2.43±0.15

>0.05

LVPW;d (mm)

0.71±0.04

0.9±0.06

*<0.01

LVPW;s (mm)

1.14±0.05

1.34±10.08

*<0.01

IVS;d (mm)

0.75±0.01

0.99±0.03

*<0.01

IVS;s (mm)

1.18±0.04

1.36±0.05

*<0.05

EF (%)

72±2.1

69±2.9

>0.05

FS (%)

41±1.8

38±2.4

>0.05

Volume;d (μl)

56±2.7

63±3.4

>0.05

Volume;s (μl)

15.9±1.6

20.5±2.7

>0.05

SV (μl)

40±1.8

42.7±0.9

>0.05

Heart rate (BPM)

420±25

428±16

>0.05

CO (ml/min)

18±0.7

18.8±0.57

>0.05

LV mass (mg)

68.7±4.7

112.2±7.3

*<0.01

  1. Abbreviations: LVID;s and LVID;d, left ventricular dimension at systole and diastole; LVPW;s and LVPW;d, posterior wall thickness at systole and diastole; IVS;s and IVS; d, interventricular septal wall thickness (diastole and systole); EF%, Ejection fraction; FS%, fractional shortening; volume;s and volume;d, left ventricle volume at systole and diastole; SV, left ventricle stroke volume; BPM, beats per minute; CO, cardiac output.
  2. Data were expressed as mean±s.e.m., *P<0.05, n=9 in each group.