Figure 1

Kinetics of the changes in the mRNA (a) and protein levels (b) of MIP-1β in oxygen-induced retinopathy (OIR) retinas. The mRNA of MIP-1β is slightly but not significantly increased in the retinas of mice 5 days after hyperoxia (P12). The level then increases significantly, peaks at 1 day after the hypoxia and then gradually decreases (a). The protein level of MIP-1β is undetectable until 6 h after hypoxia but is then markedly increased and peaks at day 2, and then gradually decreased (b). *P<0.01 compared with normal subjects.