Figure 1

Expression of NOTCH1 and NOTCH3 in various tissues. (a) Immunohistochemical staining of adult human skin, tongue and vagina shows distinct expression in the basal cells. Membrane staining pattern is obvious (right). (b) In situ hybridization on the skin of mouse E18.5 embryo, using Notch1 RNA probe. (c) Simplified summary of the expression in the epithelium of each tissue.