Table 1 Summary of patients clinical data, derived cell lines and tumorigenicity in nude mice

From: New chondrosarcoma cell lines and mouse models to study the link between chondrogenesis and chemoresistance

Patient

Gender

Age (years)

Subtype (history)

Location (recurrence)

Grade

Resection

Survival (months)

Passage

Tumorigenicity

BCSCH01

M

83

Conv

Sternum

II

R2

2

2

Yesa, grade II

BCSCH03

F

74

Dedifferentiated

Femur (1st)

High

R0

16

>70

Noa,b,c,d

BCSCH06

M

57

Conv

Sacrum (4th)

II

R0

>44

5

NP

BCSCH30

M

46

Secondary (MO)

Femur (1st)

I

R0

>30

0

NP

BCSCH34

M

73

Conv

Tibia

III

R0

>26

28

Noa

BCSCH36

F

28

Secondary (OD)

Scapula (1st)

I

Curettage

>23

5

NP

BCSCH37

F

41

Secondary (MO)

Ischion

II

R1

>22

3

NP

BCSCH45

F

64

Conv

Femur

II

R0

>23

2

NP

BCSCH56

F

64

Conv

Humerus

III

R0

>14

>40

Noa; Yesc, grade III

BCSCH59

F

67

Conv

Femur

I

Curettage

>7

0

NP

  1. Conv, conventional central CS; MO, multiple osteochondroma; NP, not performed; OD, Ollier Disease (multiple enchondroma), R0, complete removal; R1, microscopic residues; R2, macroscopic residues.
  2. aAfter biopsy subcutaneous transplantation in Balb/c Nude mice.
  3. bAfter paratibial and intrafootpad cell injection in Balb/c Nude mice.
  4. cAfter paratibial cell injection in NMRI nude mice.
  5. dAfter paratibial cell co-injection with human mesenchymal stem cells in NMRI Nude mice.
Back to article page