Figure 8 | Laboratory Investigation

Figure 8

From: Fibroblasts induce expression of FGF4 in ovarian cancer stem-like cells/cancer-initiating cells and upregulate their tumor initiation capacity

Figure 8

Correlation between FGF4 immunoreactivity and patients’ clinical outcome or CAFs proportion. FGF4 immunoreactivity is associated with poor prognosis. (a) A total 122 of epithelial ovarian cancer tissues were immunohistochemically stained with anti-FGF4 antibody and scored by three groups according to the positivity of staining. (b) The differences of overall survival were examined for statistical significance using Fischer's test. *P-values. FGF4 immunoreactivity and CAFs ratio have certain correlation. (c) A total of 122 epithelial ovarian cancer tissues were stained with α-SMA antibody. (d) Each CAFs ratio and FGF4 positivity rate were plotted and their correlation coefficient was analyzed by CORREL function.

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