Figure 5 | Laboratory Investigation

Figure 5

From: Basal cells of the human airways acquire mesenchymal traits in idiopathic pulmonary fibrosis and in culture

Figure 5

Knockdown (KD) of p63 abrogates UG-induced EMT of VA10 cells. p63 KD cells are unable to undergo UG-induced EMT. The expression of the mesenchymal markers N-cadherin and Thy-1 is abrogated in treated KD cells, whereas scrambled control cells show a division into two cellular sub-populations much like the mother cell line VA10. The expression of Vimentin can still be detected in treated KD cells, although to a lesser extent than in treated scrambled cells. Bars 100 μm.

Back to article page