Figure 1
From: Downregulation of c-Myc is involved in TLR3-mediated tumor death of neuroblastoma xenografts
Reduction of tumor size and weight of SK-N-AS (AS) but not SK-N-DZ (DZ) xenografts in NOD/SCID mice with poly(I:C) treatment. AS cells (5 × 106) or DZ cells (1 × 107) were subcutaneously injected into NOD/SCID mice. (a) Representative AS or DZ xenografts on day 17 and day 27 are presented. (b and c) Tumor size and tumor weight of NB xenografts on day 17 were measured. AS xenografts: control group n=6, treatment group n=7. DZ xenografts: control group n=3, treatment group n=5. (d and e) Tumor size and tumor weight of NB xenografts on day 27 were measured. AS xenografts: control group n=6, treatment group n=6. DZ xenografts: control group n=7, treatment group n=7. Data are expressed as means±s.e.m. of mice in each group. Quantitative analysis of tumors was determined as described in Materials and Methods. *P<0.05 with the control group.
