Table 1 Genes analysed by targeted capture

From: Detailed molecular characterisation of acute myeloid leukaemia with a normal karyotype using targeted DNA capture

Gene ID

Chromosome

Position (Mb)

AML genes

 NRAS

1

115.2

 DNMT3A

2

25.5

 SF3B1

2

198.3

 IDH1

2

209.1

 KIT

4

55.5

 TET2

4

106.1

 CSF1R

5

149.4

 NPM1

5

170.8

 EZH2

7

148.5

 JAK2

9

5.0

 PTEN

10

89.6

 WT1

11

32.4

 MLL

11

118.3

 CBL

11

119.1

 KRAS

12

25.4

 PTPN11

12

112.9

 FLT3

13

28.6

 IDH2

15

90.6

 TP53

17

7.6

 NF1

17

29.4

 CEBPA

19

33.8

 ASXL1

20

30.9

 RUNX1

21

36.2

 KDM6A

X

44.7

Control genes

 UGT1A1

2

234.7

 PIK3CA

3

178.9

 IKZF1

7

50.3

 EGFR

7

55.1

 BRAF

7

140.4

 XRCC2

7

152.3

 PAX5

9

36.8

 TLR4

9

120.5

 CYP2D6

22

42.5

 HPRT1

X

133.6

  1. Abbreviation: AML, acute myeloid leukaemia.
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