Figure 5

Impact of VPM, RSP NFV and LPV on the CFZ entrance into the AMO-CFZ cells. (a) Residual activity of proteasome subunits visualized by activity-based probe labeling after 12 h pre-treatment with indicated compounds and subsequent 1 h treatment with 50 nM CFZ. (b) AMO-CFZ stably expressing Ub-GFP co-treated for 12 h with 10 μM concentration of indicated compounds in combination with 50 nM CFZ. Significant values <0.05 are marked with an asterisk (*).