Figure 1
From: Oxidative stress-mediated iNKT-cell activation is involved in COPD pathogenesis
Characterization of immune cells in human fluids of control donors and chronic obstructive pulmonary disease (COPD) patients. (a) Percentages of CD3− CD56+ natural killer (NK), CD3+ CD56+ NKT-like and CD3+ PBS57-loaded CD1d tetramer+ iNKT cells, and CD11c+ HLA-DR+ myeloid dendritic cell (DC) were evaluated in the peripheral blood of seven healthy controls (white bars) and 28 COPD patients (black bars). The ΔMFI of the activation markers CD69 relative to isotype controls was analyzed on NK, and NKT-like cells. (b) Percentages of CD11c+ HLA-DR+ myeloid DC were evaluated in blood of healthy controls (white bars) and COPD patients (black bars). The ΔMFI of the activation markers CD86 relative to isotype controls was analyzed on DC. Gates were respectively drawn according to isotype controls, or unloaded CD1d tetramer. Data represent the mean±s.e.m. *P<0.05.
