Figure 1
Impact of experimental helicobacter chronic infection on the control of Mycobacterium tuberculosis growth. (a) Experimental chronic infection of the digestive tract by Helicobacter hepaticus, as determined by helicobacter-specific PCR on the fecal matter DNA of B10.D2 mice at 2 months after gavage with H. hepaticus 3B1 strain. (b) Control mice gavaged with peptone (Pept.) broth (n=6) or H. hepaticus 3B1 strain (n=10) were challenged with M. tuberculosis, and mycobacterial loads were determined at 8 weeks post challenge. *P<0.05, NS, nonsignificantly different, as determined by Student’s t-test and Mann–Whitney tests. Error bars represent mean±s.d. The results are representative of at least two independent experiments. CFU, colony-forming unit.
