Figure 2
From: Norovirus antagonism of B-cell antigen presentation results in impaired control of acute infection
B cells control acute MNV-1, but not MNV-3, infection. Groups of B6 (gray bars) and μMT (white bars) mice were infected p.o. with 107 TCID50 units MNV-1 (a) or MNV-3 (b). At 3, 5, 7, 10, and 14 d.p.i., the indicated tissues were dissected and virus titers were determined by plaque assay. The data are reported as pfu per gram of tissue and the data for all mice per condition (n=5–9 mice over three experiments) are averaged. Dashed lines indicate the limit of detection for each tissue. The two mouse strains were compared at each time point for each tissue for statistical purposes. d.p.i., days post infection; p.o., perorally.
