Figure 8
From: Norovirus antagonism of B-cell antigen presentation results in impaired control of acute infection
The role of B cells in MNV-1 clearance is independent of CD8+ T cells, B2M, and GrA/B. Groups of B6 (black bars), μMT (dark gray bars), CD8−/− (light gray bars), B2M−/− (white bars), 129 (white hatched bars), and GrA/B−/− (gray hatched bars) mice were infected p.o. with 107 TCID50 units MNV-1. At 14 d.p.i., the tissues indicated on the x axis were dissected and viral titers determined by plaque assay. The data are reported as pfu per gram of tissue and the data for all mice per group (n=5 per condition over two experiments) are averaged. d.p.i., days post infection; GrA/B, granzyme A/B; p.o., perorally.
