Figure 2
From: Composition and dynamics of the uterine NK cell KIR repertoire in menstrual blood
Menstrual blood uterine NK cells express high levels of KIRs. (a) Representative staining for KIR2DL1, KIR2DL1/S1, KIR2DL2/L3/S2, KIR2DL3, KIR2DS4, and KIR3DL1 on NK cells from menstrual (MBMC) and peripheral (PBMC) blood. (b) Frequency of pan-KIR+ cells (defined by Boolean-combinations of KIR gates) within subsets defined by different combinations of CD16, CD57, and NKG2A in menstrual and peripheral blood NK cells (defined as in Figure 1, n=25). (c) Frequency of cells expressing different combinations of CD16, CD57, and NKG2A in menstrual and peripheral blood (n=25) after gating on pan-KIR+ cells NK cells. (d) Frequency of menstrual blood uterine (CD16−CD57−NKG2A+) and conventional (CD16+) NK cells, and peripheral blood CD16+CD56dim NK cells expressing the indicated KIR (n=23, 9, 10, 18, 11, and 20, respectively, *P<0.05, ***P<0.001, ANOVA non-parametric test with Dunn’s test).
