Figure 7
From: Protective role of γδ T cells in cigarette smoke and influenza infection
Reduced anti-viral immune responses in Tcrδ−/− mice exposed to smoke and influenza. (a) Total lung mRNA expressions of Ifn-γ, Irf-7, and Gzmb at day 14 in the same group of mice on day 14 following influenza infection (n=4 to 8 mice per group). *P<0.05, **P<0.01, ***P<0.001. (b) Quantification of anti-hemagglutinin (HA)-specific IgG or IgA antibody using lung homogenates in the same four groups. Pooled data from two separate experiments are presented as mean±s.e.m. and significance was assessed using the Student’s t-test. *P<0.05, **P<0.01 (n=4 to 7 mice per group). (c) Selective cytokines and chemokines concentration was measured in lung homogenates using Multiplex assay in the same group (n=4 to 8 mice per group). *P<0.05 as determined using the Student’s t-test with Bonferroni correction for multiple comparisons.
