Table 1 Endometrial adenocarcinoma and myoinvasion was much more likely to be found in subsequent hysterectomy in cases with complex atypical endometrial hyperplasia on endometrial biopsy if adenocarcinoma-in situ was present in prior endometrial biopsy

From: Presence of endometrial adenocarcinoma in situ in complex atypical endometrial hyperplasia is associated with increased incidence of endometrial carcinoma in subsequent hysterectomy

Feature

CAH with AIS (%)

CAH without AIS (%)

Carcinoma in hysterectomy

22/33 (66)

13/54 (24)

Myoinvasive carcinoma

20/33 (61)

8/54 (15)

Myoinvasive carcinoma≥2 mm deep

20/33 (61)

6/54 (11)

Myoinvasive carcinoma≥3 mm deep

15/33 (45)

2/54 (4)

Myoinvasive carcinoma>50% deep

3/33 (9)

0/54 (0)

  1. Abbreviations: CAH, complex atypical hyperplasia; AIS, adenocarcinoma in situ.
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