Figure 2
From: CDKN2A–CDKN2B deletion defines an aggressive subset of cutaneous T-cell lymphoma
Interphase fluorescent in situ hybridization with Spectrum Green (CEP-9) and Spectrum Orange (9p21 locus) probes. (a) Blood sample from case-22 showing hemizygous deletion at the 9p21 locus in 40% of cells. (b) Homozygous deletion observed in 70% of blood cells from case-21. (c, d) Two green (G) and two red (R) patterns observed in 85% of blood cells from case-18, suggesting no deletion, although red signals were lower (arrowheads) than that in normal cells.
